The star, real name Stefani Germanotta, showcased a number of her other songs including Poker Face, LoveGame, Dance In The Dark, The Fame, Telephone and Applause amongst others.

She sung a total of 21 songs yesterday evening at the Park MGM hotel in Sin City.

Gaga shared a sneak peak of herself backstage with fans as she prepared to go on stage ahead of her performance.

She could be seen wearing a mirrored bodysuit which glistened in the light as she donned a bright blue wig while her lips were painted a vivid red.

7The singer performed songs spanning her career on the first nightCredit: Getty – Contributor7The star performed her debut single Just Dance as well as other hits from her first albumCredit: Getty – Contributor7The star will be putting on two different shows during her residencyCredit: Getty – Contributor

The musician adjusted her microphone as she prepared to walk out and address her adoring crowd.

The pop star wrote on Twitter: “About to step out. I can hear you. I’m so excited. I love you. Welcome to #ENIGMA.”

7Gaga fans swarmed the new venue to see the showCredit: Getty – Contributor7Lady Gaga released her first single 10 years agoCredit: Getty – Contributor

The pop superstar impressed fans as she swung on wires from the ceiling and played a number of instruments including guitar and piano.

Six-time Grammy Award-winner Gaga’s residency consists of two separate shows: Lady Gaga Enigma and Lady Gaga Jazz & Piano, during which she will perform stripped-down versions of her hits alongside music from the Great American Songbook.

Ahead of the launch, she said: “I can’t wait to share Enigma with all of my fans and with Las Vegas.

7The singer said she was looking forward to performing for her fans before taking to the stageCredit: Getty – Contributor

“We’re creating a show unlike anything I’ve done before. It will be a celebration of all that is unique and different within us.

“The challenges of bravery can be overcome with creativity and courage that is grown out of adversity, love and music.”